Description
ATP1B1 belongs to the family of Na+ /K+ and H+ /K+ -ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+ /K+ -ATPase. Na+ /K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. Na+ /K+ -ATPase is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). ATP1B1 regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. ATP1B1 is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane.
This Human ATP1B1 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of ATP1B1 protein from the overexpression lysate was verified